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It is normal in Windows to create a satellite DLL with just resources and, at run time, select the appropriate DLL by examining the language in which the operating system is running using the GetUserDefaultUILanguage API. When coding for localization, both the strings and the resource de nitions are normally placed into a single resource le per language and then that le is localized into the required languages. The resource le is then compiled and linked into a DLL. Symbian has a different process for localizing resources based on the way the toolchain and resource compilers function. The resource le contains the resource de nitions and is language neutral. Language-speci c strings are identi ed by a macro include from a separate le. There is then one le of strings per supported language and the MMP le contains a keyword indicating which languages should be built. The resource le compiler selects the appropriate language le for the language being compiled and generates a resource le for each language required. This le has an extension indicating the language. For example, English resources have the extension .r01. The Symbian run-time engine selects the appropriate language by using BaflUtils::GetNearestLanguage(). The most used localization function in Windows is LoadString(). The equivalent in Symbian is called StringLoader and offers a number of additional formatting APIs over the Win32 equivalent. It is up to the package creator how the languages are deployed. The installation script les need to be localized to support multiple languages, either by installing all the languages and allowing the operating system

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By centralizing the point at which method requests are generated, the Active Object pattern implementation can be simplified because it has fewer components. The drawback, of course, is that a scheduler must know the type of the servant and proxy, which makes it hard to reuse the same scheduler for different types of active objects. Message Passing. A further refinement of the integrated scheduler variant is to remove the proxy and servant altogether and use direct message passing between the client thread and the active object's scheduler thread.

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Isolated reports of unusual side effects came with widespread use of sulfa drugs.18 Very high doses caused some patients to excrete water and others to show a drop in blood sugar levels. Chemists in pharmaceutical laboratories seized on these apparent side effects to develop entirely new classes of drugs. By manipulating the chemical structures, scientists at Hoechst came up with a compound that normalized blood sugar in adult onset diabetics. This drug, chlorpropamide, in which the all-essential amino group is replaced by methyl, is virtually devoid of antibacterial activity. Replacement of the sulfonamide (SO2NH2) by a sulfonylurea function (SO2NHCONH2) proved crucial for antidiabetic activity and was present in the widely marketed drug tolbutamide.19 The only drugs available in the 1940s for treating conditions that required loss of body water, the diuretics, included mercury in their chemical composition. Scientists at Merck, led by Sprague, were able to introduce changes on the structure of the sulfa drugs to produce a well-tolerated diuretic drug. These principally involved adding an additional sulfonamide onto the parent molecule. This compound, chloraminophenamide, also devoid of antibacterial activity, is no longer in use. It has been superseded by hydrochlorothiazide, which was rst synthesized by chemists at Ciba. This drug, often better known by its acronym, HCTZ (Fig. 6), is still used as rst-line treatment of patients with mildly elevated blood pressure.20 The discovery of penicillin led to the recognition of the ability of fungi to protect themselves against microorganisms by secreting compounds that inhibit bacterial replication and in fact often kill off those threatening organisms. Penicillin itself showed that such antibiotics may act speci cally on enzymes that do not have counterparts in mammals. This property, shared with the sulfa drugs, led to low toxicity to humans. The search for new molecules in this class turned to the

number, employee identi cation number, and state of employment to mention a few basic ones. Form W-4 information including the state equivalents plus allowances for any reciprocal agreements or multistate withholding. It must also allow for exempt status if the employee requests it. Form W-5 information. Visa information, including the capability to block certain taxes, is required under visa regulations. Direct deposit information.

our objective world, humans can draw from events of the distant past and project to those of the distant future The symbolic units and syntax of our language provide us with a powerful instrumentality for thought and communication Each family constructs its own style of communication, its own pattern of listening and attending, and its own way of fashioning thoughts and conveying them to others The styles of interpersonal communication to which the child is exposed serve as a model for attending, organizing, and reacting to the expressions, thoughts, and feelings of others Unless this framework for learning interpersonal communication is rational and reciprocal, the child will be ill-equipped to function in an effective way with others.

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